Automatica Special Issue on Systems Biology

The 21st century has been recognized as the century of biology, and new technologies and methods are vastly accelerating the pace of discovery in biology and medicine with a growing impact on our lives. New developments and discoveries in biology do, however, often depend on an interdisciplinary approach that encompasses, among others, chemistry, physics, mathematics and the systems sciences. These interdisciplinary approaches have led to more integrative and more holistic analyses, in which not only the components are studied, but the connections be-tween, and regulations of the components are important. This approach has come to be known as "systems biology", and systems sciences have played a crucial role in that field. In this special issue, the role of systems and control theory for systems biology is emphasized. The objective is to present the latest results in this field, to highlight the contributions of the systems and control community to systems biology, and to attract further interest to systems biology from this community.

The call for papers for the special issue was very well received, and a total number of 53 papers were submitted. This pleasing response shows the growing interest of the systems and control community in the area of systems biology. Out of the submitted papers, 23 contributions have been included in this special issue and a number of additional papers have been transferred to regular issues of the journal.

Frank Allgöwer and Frank Doyle

Guest Editors

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